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ML162 derivatives incorporating a naphthoquinone unit as ferroptosis/apoptosis inducers: design, synthesis, anti-cancer activity, and drug-resistance reversal evaluation

Importantly, conversion to the fluorothioacetamide ( 15 ) restored potency to IC 50 = 1.75 0.81 M, bringing it into a similar range of cellular potency as the parent drug

This brochure includes the following recommendation: Do not test for amylase in cases of suspected acute pancreatitis

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